More on Brain Laterality and Attention Deficit Disorder
I recently wrote about the connections between attention deficit disorder and disturbances of the normal lateralization of the brain.
I had a very interesting question from a correspondent:
"Is there any CHANGE in handedness related to the use of stimulant medication?
I have been taking dexadrine (RP: That’s methamphetamine) at 60 mg/day for several months now to address ADD after diagnosis as an adult. I have found that I now use my left hand for some tasks that I would have solely used my right hand previously. For example, I am painting trim with a brush at home currently and have found myself, without forethought, switching hands and cutting in against the walls and other paint colours with my left hand at a skill level that matches my right hand. Is it possible that this is the result of increased "cross-talk" between the hemispheres? My father was not classically ambidextrous but he did play hockey and golf as a "lefty" while writing using his right hand.”
This is a fascinating question. There is evidence of shifts of functional lateralization in a number of situations, including severe changes in mood.
There is also some experimental data to support what the writer’s observations, though most of it comes from research in children.
- A study from the Netherlands showed that in children treated with methylphenidate, their manual dexterity and handwriting improved and became more accurate.
- Research from Germany using high density magnetoencephalography (MEG), showed that treatment improved activity in the frontal lobes of the brain.
- Investigators in New Mexico found that unmedicated children with ADHD had slower reaction time in their legs, which got better, particularly in the right leg, when they were given treatment.
- Another study, this time from Israel, also showed that children with ADHD had a lateralized attentional deficit that got better when they were treated.
- Children off treatment seem to have lower activity in the right hemisphere of the brain, which normalizes with treatment.
- Stimulant medications do not themselves seem to have an impact on inter-hemispheric transfer. But what it may do is to improve the imbalance between the hemispheres.
So I would suspect that the writer’s brain is becoming generally more efficient.
And his letter has also suggested a small research project.
I sense a grant proposal in our near future.